Christmas Tree The article deals with the process of torque camshaft at a constant speed.The method of release was determined by the normal force acting between the cam and the tappet.Subsequently, was expressed torque.A prerequisite for the calculations are a constant friction coefficient between the components of the mechanism and constant speed
Human leukocyte antigen evolutionary divergence as a novel risk factor for donor selection in acute lymphoblastic leukemia patients undergoing haploidentical hematopoietic stem cell transplantation
IntroductionThe human leukocyte antigen (HLA) evolutionary divergence (HED) reflects immunopeptidome diversity and has been shown to predict the response of tumors to immunotherapy.Its impact on allogeneic hematopoietic stem cell transplantation (HSCT) is controversial in different studies.MethodsIn this study, we retrospectively analyzed the clini
Epigenetic Control of Regulatory T Cell Stability and Function: Implications for Translation
FoxP3+ regulatory T (Treg) cells maintain immune homeostasis, promote self-tolerance, and have an emerging role in resolving acute inflammation, providing tissue protection, and repairing tissue damage.Some data suggest that FoxP3+ T cells are plastic, exhibiting susceptibility to losing their function in inflammatory cytokine-rich microenvironment